HCID 57669984, compound → 3-{4-[(4S,5R)-2-(2-tert-Butyl-4-ethoxy-pyrimidin-5-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-propane-1-sulfonic acid amide

Participants

Role	Name	HCID	Charge
Reactant	HCID 57669984	HCID 57669984	—
Reactant	3-Piperazin-1-yl-propane-1-sulfonic acid amide dihydrochloride	HCID 67204508	—
Product	3-{4-[(4S,5R)-2-(2-tert-Butyl-4-ethoxy-pyrimidin-5-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-propane-1-sulfonic acid amide	HCID 25261979	—

Reaction Steps

In a manner analogous to the method described in example 3, (4S,5R)-2-(2-tert-butyl-4-ethoxy-pyrimidin-5-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 2) was reacted with 3-piperazin-1-yl-propane-1-sulfonic acid amide dihydrochloride (example 55) to give the title compound. HR-MS (ES, m/z) calculated for C35H46Cl2N7O4S [(M+H)+] 730.2704, observed 730.271.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08513239B2
Source dataset	uspto-grants-2013_08
ORD ID	ord-ac818eb3773c4928b765418c9ead7601
Source note	uspto-grants-2013_08