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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894406Generated: November 2, 2026

4-(1-Pyrrolidinyl)piperidine → HCID 25260555, compound

https://huagongshe.com/reaction/1894406

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1-Pyrrolidinyl)piperidineHCID 78703—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 25260555HCID 25260555—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 4-pyrrolidin-1-yl-piperidine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C38H48Cl2N5O2 [(M+H)+] 676.318, observed 676.3176.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-ceedf3c93ee242149d66c1e907655ef5
Source noteuspto-grants-2013_08