HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperazine, (R)- → HCID 25262433, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperazine, (R)- | HCID 7330434 | — |
| Reactant | (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 57669958 | — |
| Product | HCID 25262433 | HCID 25262433 | — |
Reaction Steps
In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with (R)-2-methyl-piperazine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C34H42Cl2N5O2 [(M+H)+] 622.271, observed 622.2714.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-b58a3f2fcd3446ff9b66c0071239d768 |
| Source note | uspto-grants-2013_08 |