HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(2-Hydroxyethoxy)ethyl]piperazine → HCID 25262286, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(2-Hydroxyethoxy)ethyl]piperazine | HCID 139436 | — |
| Reactant | (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 57669958 | — |
| Product | HCID 25262286 | HCID 25262286 | — |
Reaction Steps
In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 2-(2-piperazin-1-yl-ethoxy)-ethanol (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C37H48Cl2N5O4 [(M+H)+] 696.3078, observed 696.3076.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-6f7624f89c024fafb3e207a529a8a1b5 |
| Source note | uspto-grants-2013_08 |