1-(4-Methylpiperazin-1-yl)-2-(piperazin-1-yl)ethan-1-one → HCID 57670059, compound

Participants

Role	Name	HCID	Charge
Reactant	1-(4-Methylpiperazin-1-yl)-2-(piperazin-1-yl)ethan-1-one	HCID 14090605	—
Reactant	(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride	HCID 57669958	—
Product	HCID 57670059	HCID 57670059	—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 1-(4-methylpiperazin-1-yl)-2-piperazin-1-yl-ethanone (Ibscreen-BB) to give the title compound. HR-MS (ES, m/z) calculated for C40H52Cl2N7O3 [(M+H)+] 748.3503, observed 748.3504.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08513239B2
Source dataset	uspto-grants-2013_08
ORD ID	ord-153f1363b45444c8a3ae61c2a0b0aaec
Source note	uspto-grants-2013_08