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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894432Generated: October 31, 2026

2-Amino-2-methyl-1-propanol → HCID 57670016, compound

https://huagongshe.com/reaction/1894432

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-2-methyl-1-propanolHCID 11807—
Reactant{4-[(4S,5R)-2-(6-tert-Butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochlorideHCID 25262898—
ProductHCID 57670016HCID 57670016—

Reaction Steps

In a manner analogous to the method described in examples 99, {4-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochloride (example 94) was coupled with 2-amino-2-methyl-propan-1-ol (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C39H51Cl2N6O4 [(M+H)+] 737.3344, observed 737.3342.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-96285e00afd745fdbab79d3f4421d888
Source noteuspto-grants-2013_08