HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1,3-propanediol → HCID 57669921, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1,3-propanediol | HCID 1531 | — |
| Reactant | {4-[(4S,5R)-2-(6-tert-Butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochloride | HCID 25262898 | — |
| Product | HCID 57669921 | HCID 57669921 | — |
Reaction Steps
In a manner analogous to the method described in examples 99, {4-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochloride (example 94) was coupled with 2-amino-2-methyl-propane-1,3-diol (Fluka) to give the title compound. HR-MS (ES, m/z) calculated for C39H51Cl2N6O5 [(M+H)+] 753.3293, observed 753.3292.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-e204edc55e83488ab4c4e04d6487794d |
| Source note | uspto-grants-2013_08 |