HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-oxo-2-piperidin-1-ylethyl)piperazine → HCID 57669976, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-oxo-2-piperidin-1-ylethyl)piperazine | HCID 2760439 | — |
| Reactant | (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride | HCID 57669958 | — |
| Product | HCID 57669976 | HCID 57669976 | — |
Reaction Steps
In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 2-piperazin-1-yl-1-piperidin-1-yl-ethanone (Oakwood) to give the title compound. HR-MS (ES, m/z) calculated for C40H51Cl2N6O3 [(M+H)+] 733.3394, observed 733.3392.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-660c49d7067244bd8dfe1b7eec16bd6b |
| Source note | uspto-grants-2013_08 |