4-Aminopyridine → HCID 57669903, compound

Participants

Role	Name	HCID	Charge
Reactant	4-Aminopyridine	HCID 1727	—
Reactant	{4-[(4S,5R)-2-(6-tert-Butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochloride	HCID 25262898	—
Product	HCID 57669903	HCID 57669903	—

Reaction Steps

In a manner analogous to the method described in examples 99, {4-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl )-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochloride (example 94) was coupled with pyridin-4-ylamine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C40H46Cl2N7O3 [(M+H)+] 742.3034, observed 742.3036.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08513239B2
Source dataset	uspto-grants-2013_08
ORD ID	ord-ddea18045b074ce587f3317d7b35f728
Source note	uspto-grants-2013_08