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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894466Generated: October 31, 2026

3-Amino-2-methoxypyridine → HCID 57669950, compound

https://huagongshe.com/reaction/1894466

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-2-methoxypyridineHCID 2737488—
Reactant{4-[(4S,5R)-2-(6-tert-Butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochlorideHCID 25262898—
ProductHCID 57669950HCID 57669950—

Reaction Steps

In a manner analogous to the method described in examples 99, {4-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochloride (example 94) was coupled with 2-methoxy-pyridin-3-ylamine (Fluorochem) to give the title compound. HR-MS (ES, m/z) calculated for C41H48Cl2N7O4 [(M+H)+] 772.314, observed 772.3138.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-c5d69fbc28ce4b26a2ff7c8feb90c1b1
Source noteuspto-grants-2013_08