Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894471Generated: October 30, 2026

4-Morpholinopiperidine → HCID 57669989, compound

https://huagongshe.com/reaction/1894471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MorpholinopiperidineHCID 795724—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 57669989HCID 57669989—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 4-piperidin-4-yl-morpholine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C38H48Cl2N5O3 [(M+H)+] 692.3129, observed 692.3123.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-a6982d4febed4735bd021edd5d900832
Source noteuspto-grants-2013_08