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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894483Generated: October 30, 2026

N,N-diethylpiperidin-4-amine → HCID 57670153, compound

https://huagongshe.com/reaction/1894483

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-diethylpiperidin-4-amineHCID 2758239—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 57670153HCID 57670153—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with diethyl-4-piperidinylamine (Astatech) to give the title compound. HR-MS (ES, m/z) calculated for C38H50Cl2N5O2 [(M+H)+] 678.3336, observed 678.3335.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-4c79d95dbcdd42ebaa0d1f1a8b82e5e6
Source noteuspto-grants-2013_08