Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894494Generated: October 31, 2026

Piperazin-2-one → HCID 57670041, compound

https://huagongshe.com/reaction/1894494

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazin-2-oneHCID 231360—
Reactantrac-(4S*,5R*)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 76588499—
ProductHCID 57670041HCID 57670041—

Reaction Steps

In a manner analogous to the method described in examples 8, rac-(4S*,5R*)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was coupled with 2-piperazinone (Alfa) to give the title compound. HR-MS (ES, m/z) calculated for C33H38Cl2N5O3 [(M+H)+] 622.2346, observed 622.2341.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-cfebf2946ef444cfab76e7aeddba03f4
Source noteuspto-grants-2013_08