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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894495Generated: October 30, 2026

Morpholin-4-yl-piperazin-1-yl-methanone → HCID 57669970, compound

https://huagongshe.com/reaction/1894495

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholin-4-yl-piperazin-1-yl-methanoneHCID 700139—
Reactantrac-(4S*,5R*)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 76588499—
ProductHCID 57669970HCID 57669970—

Reaction Steps

In a manner analogous to the method described in examples 8, rac-(4S*,5R*)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride was coupled with morpholin-4-yl-piperazin-1-yl-methanone (Oakwood) to give the title compound. HR-MS (ES, m/z) calculated for C38H47Cl2N6O4 [(M+H)+] 721.3031, observed 721.3031.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-057a250c5bf145a0a962a440c61d5c18
Source noteuspto-grants-2013_08