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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894497Generated: October 30, 2026

2-(Piperidin-4-yl)acetamide → HCID 57406666, compound

https://huagongshe.com/reaction/1894497

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Piperidin-4-yl)acetamideHCID 22064934—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 57406666HCID 57406666—

Reaction Steps

In a manner analogous to the method described in examples 8, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was coupled with 2-piperidin-4-yl-acetamide (ChemBridge) to give the title compound. HR-MS (ES, m/z) calculated for C36H44Cl2N5O3 [(M+H)+] 664.2816, observed 664.2818.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-40252196d8c044b791dd395d48ea585a
Source noteuspto-grants-2013_08