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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894519Generated: November 4, 2026

4-Piperidone → HCID 57670001, compound

https://huagongshe.com/reaction/1894519

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidoneHCID 33721—
Reactant(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57669958—
ProductHCID 57670001HCID 57670001—

Reaction Steps

In a manner analogous to the method described in example 3, (4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride (example 51) was reacted with piperidin-4-one (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C34H39Cl2N4O3 [(M+H)+] 621.2394, observed 621.2395.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-096d93d33fa943c0b2a3318c79abb503
Source noteuspto-grants-2013_08