HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → HCID 57669941, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | (4-amino-piperidin-1-yl)-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazol-1-yl]-methanone | HCID 57669927 | — |
| Product | HCID 57669941 | HCID 57669941 | — |
Reaction Steps
(4-Amino-piperidin-1-yl)-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazol-1-yl]-methanone (example 204) was reacted with phosgene (Fluka) and pyrrolidine (Aldrich) to give the title product. LC-MS (ES+) 719 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-9502d4ad20ea499ea7e27d611c1293fd |
| Source note | uspto-grants-2013_08 |