Dimethylamine → HCID 57670113, compound

Participants

Role	Name	HCID	Charge
Reactant	Dimethylamine	HCID 674	—
Reactant	Phosgene	HCID 6371	—
Reactant	(4-amino-piperidin-1-yl)-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazol-1-yl]-methanone	HCID 57669927	—
Product	HCID 57670113	HCID 57670113	—

Reaction Steps

(4-Amino-piperidin-1-yl)-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazol-1-yl]-methanone (example 204) was reacted with phosgene (Fluka) and dimethylamine (Aldrich) to give the title product. LC-MS (ES+) 693 [(M+H)+].

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08513239B2
Source dataset	uspto-grants-2013_08
ORD ID	ord-3a3d24ff90f74325b00d626c609b6438
Source note	uspto-grants-2013_08