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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894538Generated: November 1, 2026

3-Methoxy-N-(3-methoxypropyl)-1-propanamine → HCID 57670127, compound

https://huagongshe.com/reaction/1894538

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methoxy-N-(3-methoxypropyl)-1-propanamineHCID 18320509—
Reactant{1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acidHCID 57670162—
ProductHCID 57670127HCID 57670127—

Reaction Steps

In a manner analogous to the method described in example 163, {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid was coupled with bis-(3-methoxy-propyl)-amine (prepared from bis-(3-chloro-propyl)-amine and sodium methoxide) to give the title compound. HR-MS (ES, m/z) calculated for C44H59Cl2N5O5 [(M+H)+] 808.3966, observed 808.3965.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-e33d34f23792456d86d1dfb5fd2344b8
Source noteuspto-grants-2013_08