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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894552Generated: October 31, 2026

Benzenemethanamine, 3-chloro- → HCID 57669911, compound

https://huagongshe.com/reaction/1894552

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenemethanamine, 3-chloro-HCID 77802—
Reactant{1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acidHCID 57670162—
ProductHCID 57669911HCID 57669911—

Reaction Steps

In a manner analogous to the method described in example 163, {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid was coupled with 3-chloro-benzylamine (Avocado) to give the title compound. HR-MS (ES, m/z) calculated for C43H49Cl3N5O3 [(M+H)+] 788.2896, observed 788.2890.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-5e894372e9344f0cba1a1c9096bb749e
Source noteuspto-grants-2013_08