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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894553Generated: October 31, 2026

2-Fluorobenzylamine → HCID 57669961, compound

https://huagongshe.com/reaction/1894553

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorobenzylamineHCID 66649—
Reactant{1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acidHCID 57670162—
ProductHCID 57669961HCID 57669961—

Reaction Steps

In a manner analogous to the method described in example 163, {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid was coupled with 2-fluoro-benzylamine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C43H49Cl2FN5O3 [(M+H)+] 772.3191, observed 772.3185.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-2b0dc63d3e3a4a9e88b69bb8df6d5bb9
Source noteuspto-grants-2013_08