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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894557Generated: November 1, 2026

(S)-(+)-1-Cyclohexylethylamine → HCID 57669918, compound

https://huagongshe.com/reaction/1894557

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-(+)-1-CyclohexylethylamineHCID 5325951—
Reactant{1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acidHCID 57670162—
ProductHCID 57669918HCID 57669918—

Reaction Steps

In a manner analogous to the method described in example 163, {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid was coupled with N-((S)-1-cyclohexyl-ethyl)amine (Aldrich) to give the title compound. HR-MS (ES, m/z) calculated for C44H58Cl2N5O3 [(M+H)+] 774.391 1, observed 774.3913.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-39c5161dcead430b97cc6a9563eb8698
Source noteuspto-grants-2013_08