HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoindoline → HCID 57670079, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoindoline | HCID 422478 | — |
| Reactant | {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid | HCID 57670162 | — |
| Product | HCID 57670079 | HCID 57670079 | — |
Reaction Steps
In a manner analogous to the method described in example 163, {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid was coupled with 2,3-dihydro-1H-isoindole (Oakwood) to give the title compound. HR-MS (ES, m/z) calculated for C44H50Cl2N5O3 [(M+H)+] 766.3285, observed 766.3286.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-e22d65df6ca643c58bd51ecfe10195e9 |
| Source note | uspto-grants-2013_08 |