Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894560Generated: October 26, 2026

(S)-1-(2-Fluorophenyl)ethylamine → HCID 57670091, compound

https://huagongshe.com/reaction/1894560

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-1-(2-Fluorophenyl)ethylamineHCID 7023579—
Reactant{1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acidHCID 57670162—
ProductHCID 57670091HCID 57670091—

Reaction Steps

In a manner analogous to the method described in example 163, {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid was coupled with (S)-1-(2-fluoro-phenyl)-ethylamine (Matrix) to give the title compound. HR-MS (ES, m/z) calculated for C44H51Cl2FN5O3 [(M+H)+] 786.3348, observed 786.3343.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-ed1afc764d1943a59dacf06b7d9b9132
Source noteuspto-grants-2013_08