Trimethylsilyl isocyanate → HCID 57670157, compound

Participants

Reaction Steps

In a manner analogous to the method described in example 160, [(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazol-1-yl]-piperazin-1-yl-methanone (example 185) was reacted with trimethylsilyl isocyanate (TCI-US) to give the title compound. HR-MS (ES, m/z) calculated for C34H41Cl2N6O3 [(M+H)+] 651.2612, observed 651.2608.

Provenance & Evidence