HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R)-(+)-1-(4-Fluorophenyl)ethylamine → HCID 57670026, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R)-(+)-1-(4-Fluorophenyl)ethylamine | HCID 6950187 | — |
| Reactant | {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid | HCID 57670162 | — |
| Product | HCID 57670026 | HCID 57670026 | — |
Reaction Steps
In a manner analogous to the method described in example 163, {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid was reacted with (R)-1-(4-fluorophenyl)ethylamine (Alfa) to give the title product. LC-MS (ES+) 786 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513239B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-0ccf68289bf54392a47e0f16604113d2 |
| Source note | uspto-grants-2013_08 |