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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1894629Generated: October 31, 2026

(1R)-(+)-1-(4-Fluorophenyl)ethylamine → HCID 57670026, compound

https://huagongshe.com/reaction/1894629

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R)-(+)-1-(4-Fluorophenyl)ethylamineHCID 6950187—
Reactant{1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acidHCID 57670162—
ProductHCID 57670026HCID 57670026—

Reaction Steps

In a manner analogous to the method described in example 163, {1-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperidin-4-yl}-acetic acid was reacted with (R)-1-(4-fluorophenyl)ethylamine (Alfa) to give the title product. LC-MS (ES+) 786 [(M+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513239B2
Source datasetuspto-grants-2013_08
ORD IDord-0ccf68289bf54392a47e0f16604113d2
Source noteuspto-grants-2013_08