Sodium Hydroxide → HCID 44159846, compound

HRID 1894696Notes

Reaction equation

HRID 1894696 reaction equation
C(O)(=O)C(O)=O.[NH2:7][C:8]1[C:13]([C:14]2[O:18][N:17]=[C:16]([CH2:19][OH:20])[CH:15]=2)=[CH:12][CH:11]=[CH:10][N:9]=1.[OH-].[Na+]>O>[NH2:7][C:8]1[C:13]([C:14]2[O:18][N:17]=[C:16]([CH2:19][OH:20])[CH:15]=2)=[CH:12][CH:11]=[CH:10][N:9]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 67355904HCID 67355904, compound

Product 1

HCID 44159846HCID 44159846, compoundYield 67.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a mixture of [5-(2-aminopyridin-3-yl)isoxazol-3-yl]methanol oxalate (0.39 g) and water (2 mL) was added 5N aqueous sodium hydroxide (0.5 mL) at room temperature and the precipitated solid was filtered to obtain the title compound (0.18 g) as a white solid.

Workup

  1. filtrationthe precipitated solid was filtered

Sources & evidence

ORD record
ord-8e21b0aa221943668ee771bd579f361a
Source dataset
uspto-grants-2013_08
Patent number
US08513287B2

Reaction notes

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