Sodium Azide → HCID 86662135, compound

Participants

Reaction Steps

To a 1 mL DMF solution of 2-(chloromethyl)-5-(1H-pyrazol-5-yl)-1,3,4-thiadiazole (58 mg, 0.29 mmol) was added sodium azide (20 mg, 0.30 mmol). Stirring continued at rt for 3 hr. The reaction mixture was concentrated and diluted with AcOEt and water. The organic layer was separated. The aqueous layer was extracted with AcOEt twice and the combined organic layers were dried over anhydrous sodium sulfate, filtered, and concentrated to give the title compound (60 mg).

Provenance & Evidence