HCID 59409006, compound → HCID 59409001, compound

Participants

Reaction Steps

3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-8-yl)-4-(1H-indol-3-yl)-pyrrole-2,5-dione (753 mg, 2.05 mmol) and 5% palladium on carbon (100 mg) in methanol (40 ml) were stirred under hydrogen at 60 psi for 15 hours at room temperature. The reaction mixture was filtered through a bed of celite and the filtrate evaporated to dryness to afford (±)-cis-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-8-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione (760 mg) which was used without further purification. LCMS: 370 [M+H].

Provenance & Evidence