Bromopyruvic Acid → HCID 80568044, compound

HRID 1895386Notes

Reaction equation

HRID 1895386 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][C:8]([NH2:10])=[S:9].Br[CH2:12][C:13](=O)[C:14]([OH:16])=[O:15]>>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][NH:7][C:8]1[S:9][CH:12]=[C:13]([C:14]([OH:16])=[O:15])[N:10]=1

Participants

3

Reactant 2

HCID 70684Bromopyruvic AcidHCID 7176991-(2-Furfuryl)-2-thiourea

Product 1

HCID 80568044HCID 80568044, compoundYield 98.2%

Procedure

2-[(Furan-2-ylmethyl)-amino]-thiazole-4-carboxylic acid (220 mg) was prepared according to General Procedure B using furan-2-ylmethyl-thiourea (156 mg) and 3-bromo-2-oxo-propionic acid (167 mg).

Sources & evidence

ORD record
ord-f29f5c9e244b4b03b687cefb3a792842
Source dataset
uspto-grants-2013_08
Patent number
US08513430B2

Reaction notes

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