HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromopyruvate → 2-(Pyridin-4-ylamino)-thiazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromopyruvate | HCID 66144 | — |
| Reactant | 4-Pyridylthiourea | HCID 2737249 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(Pyridin-4-ylamino)-thiazole-4-carboxylic acid ethyl ester | HCID 2742075 | 79.8% |
Reaction Steps
2-(Pyridin-4-ylamino)-thiazole-4-carboxylic acid ethyl ester (200 mg) was prepared according to General Procedure B using pyridin-4-yl-thiourea (154 mg) and 3-bromo-2-oxo-propionic acid ethyl ester (200 mg) in methanol (2 mL). The crude product was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513430B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-590b8093db2c4bdfb726d403ee5462a4 |
| Source note | uspto-grants-2013_08 |