HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromopyruvic Acid → 2-(3,4-Dichloroanilino)-1,3-thiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromopyruvic Acid | HCID 70684 | — |
| Reactant | N-(3,4-Dichlorophenyl)thiourea | HCID 710776 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(3,4-Dichloroanilino)-1,3-thiazole-4-carboxylic acid | HCID 24213860 | 95.6% |
Reaction Steps
2-(3,4-Dichloro-phenylamino)-thiazole-4-carboxylic acid (275 mg) was prepared according to General Procedure B using (3,4-dichloro-phenyl)-thiourea (220 mg) and 3-bromo-2-oxo-propionic acid (200 mg) in methanol (2 mL). The crude product was used in a subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513430B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-e04cea16fea34da191b2528d6ca902ee |
| Source note | uspto-grants-2013_08 |