Isopropyl 5-[acetyl-(3,5-bis-trifluoromethyl-benzyl)-amino]-9-bromo-7-methyl-2,3,4,5-tetrahydro-benzo[b]azepine-1-carboxylate → Isopropyl 5-[Acetyl-(3,5-bis-trifluoromethyl-benzyl)-amino]-7,9-dimethyl-2,3,4,5-tetrahydro-benzo[b]azepine-1-carboxylate
Reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]([CH:5]1[c:6]2[c:7]([c:18]([Br:23])[cH:19][c:20]([CH3:22])[cH:21]2)[N:8]([C:12](=[O:13])[O:14][CH:15]([CH3:16])[CH3:17])[CH2:9][CH2:10][CH2:11]1)[CH2:24][c:25]1[cH:26][c:27]([C:35]([F:36])([F:37])[F:38])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1.[C:39]([N:40]([CH2:41][c:42]1[cH:43][c:44]([C:45]([F:46])([F:47])[F:48])[cH:49][c:50]([C:51]([F:52])([F:53])[F:54])[cH:55]1)[CH:56]1[CH2:57][CH2:58][CH2:59][N:60]([C:61]([O:62][CH:63]([CH3:64])[CH3:65])=[O:66])[c:67]2[cH:68][c:69]([CH3:70])[c:71]([CH3:72])[cH:73][c:74]21)(=[O:75])[CH3:76]>>[C:1]([CH3:2])(=[O:3])[N:4]([CH:5]1[c:6]2[c:7]([c:18]([CH3:39])[cH:19][c:20]([CH3:22])[cH:21]2)[N:8]([C:12](=[O:13])[O:14][CH:15]([CH3:16])[CH3:17])[CH2:9][CH2:10][CH2:11]1)[CH2:24][c:25]1[cH:26][c:27]([C:35]([F:36])([F:37])[F:38])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7085463e4bec40fb9192c7815f47ce62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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