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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 189551Generated: October 25, 2026

Water → 3-(2-ethoxypyridin-3-yl)-6-fluoro-3-hydroxy-2-oxo-2,3-dihydro-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/189551

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantCyanideHCID 5975—
ReactantDimethylformamideHCID 6228—
ReactantZinc(2+)HCID 32051—
Reactant5-Bromo-3-(2-ethoxypyridin-3-yl)-6-fluoro-3-hydroxy-1,3-dihydroindol-2-oneHCID 67087630—
ReactantHCID 178420554HCID 178420554—
Product3-(2-ethoxypyridin-3-yl)-6-fluoro-3-hydroxy-2-oxo-2,3-dihydro-1H-indole-5-carbonitrileHCID 67087458—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-62e35584bd1f4a5cbf1407aefb0e77e5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)