Tris(furan-2-yl)phosphane → N-[[3-[4-[6-[5-(hydroxymethyl)-4,5-dihydro-1,2-oxazol-3-yl]-3-pyridinyl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HRID 189567Notes

Reaction equation

HRID 189567 reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([C:29]2=[N:30][O:31][CH:32]([CH2:34][OH:35])[CH2:33]2)[n:27][cH:28]1.[O:1]=[C:2]1[O:3][CH:4]([CH2:17][NH:18][C:19]([CH3:20])=[O:21])[CH2:5][N:6]1[c:7]1[cH:8][cH:9][c:10]([Sn:13]([CH3:14])([CH3:15])[CH3:16])[cH:11][cH:12]1.[o:36]1[cH:37][cH:38][cH:39][c:40]1[P:41]([c:42]1[o:43][cH:44][cH:45][cH:46]1)[c:47]1[o:48][cH:49][cH:50][cH:51]1>>[O:1]=[C:2]1[O:3][CH:4]([CH2:17][NH:18][C:19]([CH3:20])=[O:21])[CH2:5][N:6]1[c:7]1[cH:8][cH:9][c:10](-[c:23]2[cH:24][cH:25][c:26]([C:29]3=[N:30][O:31][CH:32]([CH2:34][OH:35])[CH2:33]3)[n:27][cH:28]2)[cH:11][cH:12]1

Participants

4

Reactant 3

HCID 521585Tris(furan-2-yl)phosphaneHCID 17954471[3-(5-Bromopyridin-2-yl)-4,5-dihydroisoxazol-5-yl]methanolHCID 22479436N-[[2-oxo-3-(4-trimethylstannylphenyl)-1,3-oxazolidin-5-yl]methyl]acetamide

Product 1

HCID 178474579N-[[3-[4-[6-[5-(hydroxymethyl)-4,5-dihydro-1,2-oxazol-3-yl]-3-pyridinyl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Sources & evidence

ORD record
ord-4e98fcf8e2b34ef7b24cd7d44e41901c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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