Methanol → HCID 67172260, compound

Participants

Reaction Steps

The product of Step 2 (4.5 g) was dissolved in MeOH (200 mL) and 3 drops of H2SO4 were added. The mixture was heated to reflux for 3 hrs and cooled to room temperature. After evaporation of the solvent, the resulting residue was dissolved in DCM (150 mL) and washed with brine (50 mL). The organic layer was collected and the solvent evaporated to afford the product methyl 5-hydroxy-3,9-dimethyl-7H-benzo[c]fluorene-7-carboxylate (4.5 g). MS analysis supported the molecular weight of the product.

Provenance & Evidence