Isopropylamine → HCID 67044925, compound

HRID 1895831Notes

Reaction equation

HRID 1895831 reaction equation
[CH:1]([NH2:4])([CH3:3])[CH3:2].[C:5]1([P:11]([CH2:14]O)[CH2:12]O)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>>[C:5]1([P:11]([CH2:14][NH:4][CH:1]([CH3:3])[CH3:2])[CH2:12][NH:4][CH:1]([CH3:3])[CH3:2])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 201037Methanol, (phenylphosphinidene)bis- (9CI)

Product 1

HCID 67044925HCID 67044925, compound

Procedure

Degassed isopropyl amine (1 ml, 11.6 mmol) of was added to 491 mg (2.886 mmol) of (phenylphosphinediyl)dimethanol (PhP(CH2OH)2) and the mixture was stirred overnight. The excess amine was removed in vacuo to afford the product as a viscous colorless oil. 1H NMR (400 Mhz, C6D6): δ 7.55 (m, 2H); 7.09 (m, 3H); 3.11 (m, 4H); 2.68 (m, 2H); 0.89 (m, 12H). 31P NMR (162 Mhz, C6D6): −29.5.

Workup

  1. customThe excess amine was removed in vacuo

Sources & evidence

ORD record
ord-a583233d5f4845ef93cf9fbc4d3cba8f
Source dataset
uspto-grants-2013_08
Patent number
US08518368B2

Reaction notes

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