Triethylamine → HCID 86652726, compound

Participants

Reaction Steps

Ethyl chlorooxoacetate (0.145 ml, 1.30 mmol) was added to a solution of O-(1-(4-(trifluoromethoxy)phenylsulfonyl)piperidin-4-yl)hydroxylamine (390 mg, 1.15 mmol) and triethylamine (0.246 ml, 1.76 mmol) in CH2Cl2 (8 ml) and stirred at room temperature for 2 hours. The reaction mixture was diluted with CH2Cl2 and washed with aqueous NaHCO3 solution (10 ml) and concentrated in vacuo to give crude product of N-[1-(4-trifluoromethoxybenzenesulfonyl)piperidin-4-yloxy]oxalamic acid ethyl ester.

Provenance & Evidence