4-Toluenesulfonyl chloride → HCID 87550393, compound

Participants

Reaction Steps

A solution of the Compound of Example 3 (60 mg, 0.283 mmol), p-toluenesulfonyl chloride (80.9 mg, 0.425 mmol), TEA (0.425 mmol) in 5 mL of CHCl3 was stirred at r.t. for 1 h. The chloroform solution was washed with NaOH 0.1 N, water, dried over Na2SO4 and evaporated to dryness in vacuo. Purification by flash chromatography (EtOAc—Petroleum Ether 1:1), afforded 67 mg of the title product.

Provenance & Evidence