反应详情

The title compound was prepared as described for the compound of Example 237 but starting from Compound 312b instead of Compound 237a and 2-chloro-6-methyl-3-nitropyridine instead of 2-bromo-3-nitropyridine. After the work-up, the residue was purified by automated flash liquid chromatography (Horizon™-Biotage) eluting with PE-EtOAc from PE:EtOAc 9:1 affording the title products as yellow oil. Yield: 93%.

1. customAfter the work-up, the residue was purified by automated flash liquid chromatography (Horizon™-Biotage)
2. washeluting with PE-EtOAc from PE