反应详情

A mixture of 9-(3-azidopropyl)adenine and 5% palladium on carbon in methanol was reacted with hydrogen gas at room temperature for 22 hours. The catalyst was removed by filtration, the solvent was removed to give 9-(3-aminopropyl)adenine as a white solid. The reference for the synthetic procedure is Zhang et al., “Syntheses and coordination chemistry of aminomethylphosphine derivatives of adenine,” Euro. J. Inorg. Chem. 13:2426-37, 2003, which is incorporated by reference herein in its entirety.

1. customThe catalyst was removed by filtration
2. customthe solvent was removed