2-Bromopropanedial → HCID 178419452, compound

HRID 1896430Notes

Reaction equation

HRID 1896430 reaction equation
[C:1]1([C:7]2[CH:11]=[C:10]([NH2:12])[NH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:13][CH:14]([CH:17]=O)[CH:15]=O>>[Br:13][C:14]1[CH:15]=[C:11]2[C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[N:8][NH:9][C:10]2=[N:12][CH:17]=1

Participants

3

Reactant 2

HCID 749452-BromopropanedialHCID 1366553-Amino-5-phenylpyrazole

Product 1

HCID 178419452HCID 178419452, compoundYield 13%

Procedure

5-bromo-3-phenyl-1H-pyrazolo[3,4-b]pyridine x151 is synthesized according to the method described in example 20.1 using 3-phenyl-1H-pyrazol-5-amine x150 and bromomalonaldehyde x9.

Sources & evidence

ORD record
ord-341b297ae38640218eb2c7dc92f7794a
Source dataset
uspto-grants-2013_08
Patent number
US08518943B2

Reaction notes

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