Methanol → HCID 59198417, compound

Participants

Reaction Conditions

Reaction Steps

4-Bromo-1-chloro-8-fluoro-5H-pyrido[4,3-b]indole (150 mg, 0.501 mmol) was dissolved in methylamine in methanol (3 mL, 6.00 mmol) and heated to 140° C. in the microwave for six hours. The reaction mixture was concentrated in vacuo and purified on silica gel (0-20% ethyl acetate/hexanes gradient elution).

Provenance & Evidence