Methanesulfonic Acid → HCID 23582062, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of the product of Step 3 in a 1:1 (mass/mass) mixture of PPA/CH3SO3H (0.034 M) was stirred for 90 min at 120° C. The resulting mixture was then added to ice-cold saturated NaHCO3 solution, stirring until all the reagent was consumed and the pH was 7-8. The crude material was collected by filtration, and was purified by preparative TLC, eluting with 1:20 MeOH:EtOAc to give the title compound as a white solid.

Provenance & Evidence