3-(1,3,2-Dioxaborinan-2-yl)pyridine → HCID 23582064, compound

HRID 1896554Notes

Reaction equation

HRID 1896554 reaction equation
[NH2:1][C:2]1[C:14]2[C:13]3[CH:12]=[CH:11][C:10](Cl)=[CH:9][C:8]=3[NH:7][C:6]=2[C:5]([C:16]([NH2:18])=[O:17])=[CH:4][N:3]=1.B1([C:25]2[CH:30]=[CH:29][CH:28]=[N:27][CH:26]=2)OCCCO1>>[NH2:1][C:2]1[C:14]2[C:13]3[CH:12]=[CH:11][C:10]([C:25]4[CH:26]=[N:27][CH:28]=[CH:29][CH:30]=4)=[CH:9][C:8]=3[NH:7][C:6]=2[C:5]([C:16]([NH2:18])=[O:17])=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 41980053-(1,3,2-Dioxaborinan-2-yl)pyridineHCID 23582063HCID 23582063, compound

Product 1

HCID 23582064HCID 23582064, compound

Procedure

The title compound was prepared from 1-amino-7-chloro-5H-pyrido[4,3-b]indole-4-carboxamide (Example 27, step 5) and pyridine-3-boronic acid 1,3-propanediol cyclic ester using conditions described in example 2.

Sources & evidence

ORD record
ord-b9ed55f5ad1542bc9edea09a8f6c4a23
Source dataset
uspto-grants-2013_08
Patent number
US08518964B2

Reaction notes

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