Potassium Cation → 3-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-(5-{3-methyl-3-[(triethylsilyl)oxy]butyl}-2-thienyl)-1H-indole-7-carboxamide

HRID 189660Notes

Reaction equation

HRID 189660 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([CH:14]3[CH2:15][CH2:16][S:17](=[O:20])(=[O:21])[CH2:18][CH2:19]3)[cH:6][nH:7][c:8]2[c:9]([C:11](=[O:12])[NH2:13])[cH:10]1.[C:49](=[O:50])([O-:51])[O-:52].[CH3:22][C:23]([CH2:24][CH2:25][c:26]1[s:27][c:28]([B:31]2[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]2)[cH:29][cH:30]1)([CH3:40])[O:41][Si:42]([CH2:43][CH3:44])([CH2:45][CH3:46])[CH2:47][CH3:48].[K+:53].[K+:54].[O:56]1[CH2:57][CH2:58][O:59][CH2:60][CH2:61]1.[OH2:55]>>[c:2]1(-[c:28]2[s:27][c:26]([CH2:25][CH2:24][C:23]([CH3:22])([CH3:40])[O:41][Si:42]([CH2:43][CH3:44])([CH2:45][CH3:46])[CH2:47][CH3:48])[cH:30][cH:29]2)[cH:3][c:4]2[c:5]([CH:14]3[CH2:15][CH2:16][S:17](=[O:20])(=[O:21])[CH2:18][CH2:19]3)[cH:6][nH:7][c:8]2[c:9]([C:11](=[O:12])[NH2:13])[cH:10]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 593327575-Bromo-3-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-1H-indole-7-carboxamideHCID 66746892({1,1-Dimethyl-3-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thienyl]propyl}oxy)(triethyl)silane

Product 1

HCID 593327423-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-(5-{3-methyl-3-[(triethylsilyl)oxy]butyl}-2-thienyl)-1H-indole-7-carboxamide

Sources & evidence

ORD record
ord-c6a0286f7e0340299ea8220cac6cc4fd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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