1,4-Dioxaspiro(4.5)decane-8-carbaldehyde → HCID 58562809, compound

HRID 1896836Notes

Reaction equation

HRID 1896836 reaction equation
[O:1]1[C:5]2([CH2:10][CH2:9][CH:8]([CH:11]=[O:12])[CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.[CH2:13]([Mg]Br)[CH3:14]>>[O:1]1[C:5]2([CH2:10][CH2:9][CH:8]([CH:11]([OH:12])[CH2:13][CH3:14])[CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 98989471,4-Dioxaspiro(4.5)decane-8-carbaldehydeHCID 178418443HCID 178418443, compound

Product 1

HCID 58562809HCID 58562809, compound

Procedure

Reacting 1,4-dioxaspiro[4.5]decane-8-carbaldehyde (prepared as described in Pearson, et al. in J. Org. Chem. 1997, 62(16), 5284-5292) with ethylmagnesium bromide as described in Example 2, Step A yielded the title compound.

Sources & evidence

ORD record
ord-fadb28bf4c2b4ed1a72e4e21ca8ea138
Source dataset
uspto-grants-2013_08
Patent number
US08518969B2

Reaction notes

Loading…