Methyl N-(triethylammoniosulfonyl)carbamate → HCID 12531502, compound

Participants

Reaction Conditions

Reaction Steps

To a solution 2-(1,4-dioxaspiro[4.5]decan-8-yl)propan-2-ol (164 mg, 0.82 mmol, prepared in the Example 29, Step A) in THF (10 mL) cooled to 0° C. under argon was added Burgess Reagent (214 mg, 0.87 mmol). After the complete addition, the reaction mixture was at room temperature 1 hour and then concentrated in vacuo. The residue purified by flash chromatography (silica gel, DCM) to afford the product.

Provenance & Evidence