Tert-butyl 2-(2-cyano-6-(trifluoromethyl)quinolin-4-ylamino)acetate → 2-(2-Cyano-6-(trifluoromethyl)quinolin-4-ylamino)acetic acid

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Reaction Steps

Into a 25 mL vial, was placed a solution of tert-butyl 2-(2-cyano-6-(trifluoromethyl)quinolin-4-ylamino)acetate (as prepared in the previous step, 80 mg, 0.23 mmol, 1.00 equiv) in dichloromethane (10 mL) and CF3COOH (2 mL). The reaction mixture was stirred overnight at room temperature. The resulting mixture was concentrated under vacuum. The title compound was obtained as a white solid

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