HCID 69938195, compound → HCID 86674835, compound

Participants

Reaction Steps

The racemic mixture 7 (220 mg, 0.779 mmol) was separated by HPLC (ChiralPak AS-H, 21×250 mm, 90% heptane 10% ethanol, v/v) giving (S)-2-(5-fluoro-4-(1-hydroxyethyl)pyridin-3-yl)benzofuran-5-carbonitrile 7-(enantiomer-1) as white solid (72 mg) (retention time: 10.93 min) and (R)-2-(5-fluoro-4-(1-hydroxyethyl)pyridin-3-yl)benzofuran-5-carbonitrile 7-(enantiomer-2) as white solid (66 mg) (retention time: 12.57 min).

Provenance & Evidence